Effects of Aeroallergen Sensitization on Symptom Severity, Pulmonary Function, and Bronchodilator Response in Children With Bronchial Asthma

Background: Allergen sensitization, symptom severity, pulmonary function test, and bronchodilator response are important in the diagnosis treatment of asthma. However, relationship between these factors remains unclear. Objective: The objective this study was to investigate aeroallergen sensitization asthma function, among pediatric patients with bronchial Methods: This a prospective where 155 aged 7–18 years old were recruited from Outpatient Clinics. Patients who met inclusion criteria proceeded spirometry skin prick test. Results: There significant degree wherein 100% had one or more aeroallergens. Among children, 106 (68%) polysensitized. polysensitized group severe persistent severity profile (p<0.001) worse (p<0.001). frequency abnormal pre-bronchodilator lung higher than monosensitized A positive children as compared Sensitization Dermatophagoides farinae, pteronyssinus dog correlated impairment both large airways distal small while cat, cockroach, horse only (p<0.05). sensitized D. pteronyssinus, cat Conclusion: Polysensitized asthmatic profile, reversibility group.